Embryo-Biopsy And Pre-Implantation Genetic Testing in Hyderabad
Advancements in reproductive medicine now allow fertility specialists to evaluate the genetic health of embryos before pregnancy begins. At Fertilica IVF, we offer advanced Embryo Biopsy and Pre-Implantation Genetic Testing (PGT) in Hyderabad to help couples reduce the risk of inherited genetic disorders, improve embryo selection, and increase the chances of a successful pregnancy. By combiningembryology techniques used in assisted reproductive treatment with comprehensive genetic screening, our specialists can provide genetic information that may help guide embryo-transfer decisions, helping couples achieve healthier pregnancy outcomes with greater confidence.
What is Embryo Biopsy and Pre-Implantation Genetic Testing (PGT)?
Embryo Biopsy and Pre-Implantation Genetic Testing (PGT) is an advanced genetic screening procedure performed during an IVF cycle. It involves removing a small number of cells from a developing embryo and testing them for chromosomal abnormalities or inherited genetic disorders before embryo transfer.
The procedure allows fertility specialists to identify embryos with the correct number of chromosomes and those free from specific genetic conditions. Results may inform embryo-selection decisions. PGT has limitations and does not guarantee implantation, pregnancy or the birth of a child without a genetic condition.
There are three primary types of PGT:
- PGT-A (Preimplantation Genetic Testing for Aneuploidy): Screens embryos for abnormal chromosome numbers.
- PGT-M (Preimplantation Genetic Testing for Monogenic Disorders): Detects specific inherited genetic diseases.
- PGT-SR (Preimplantation Genetic Testing for Structural Rearrangements): Identifies chromosomal translocations and structural abnormalities.
How Does Embryo Biopsy and Pre-Implantation Genetic Testing (PGT) Work?
Step 1
Fertility Assessment and Treatment Planning
A comprehensive fertility evaluation is performed to determine whether PGT is appropriate for the couple's reproductive goals.
Step 2
Ovarian Stimulation
Hormonal medications stimulate the ovaries to produce multiple eggs for fertilization.
Step 3
Egg Retrieval and Fertilization
Mature eggs are collected and fertilized in the laboratory using IVF or ICSI techniques.
Step 4
Embryo Development
The embryos are cultured for 5–6 days until they reach the blastocyst stage, which is ideal for biopsy.
Step 1
Blastocyst Biopsy
A few cells are carefully removed from the outer layer of the blastocyst (trophectoderm) without affecting the embryo's future development.
Step 2
Embryo Freezing
Following biopsy, embryos are cryopreserved while awaiting genetic testing results.
Step 3
Advanced Genetic Analysis
The biopsied cells are examined using sophisticated genetic technologies to detect chromosomal abnormalities and inherited disorders.
Step 4
Embryo Classification
Embryos are categorized based on genetic findings, helping specialists identify those suitable for transfer.
Step 1
Genetic Counselling
Results are reviewed with the couple to explain findings and discuss treatment recommendations.
Step 2
Healthy Embryo Selection
Genetically normal embryos are selected for transfer based on laboratory grading and genetic screening outcomes.
Step 3
Frozen Embryo Transfer (FET)
A healthy embryo is transferred into the uterus during a carefully prepared cycle.
Step 4
Pregnancy Monitoring
Pregnancy testing and follow-up care are provided to monitor progress after embryo transfer.
Embryo Biopsy and Pre-Implantation Genetic Testing (PGT) Success Rate in Hyderabad
PGT enhances IVF outcomes by helping fertility specialists identify chromosomally normal embryos with the genetic findings that may be relevant to embryo-transfer decisions. While PGT does not improve embryo quality itself, it improves embryo selection accuracy and may reduce miscarriage rates and failed implantation. Success rates depend on maternal age, embryo quality, ovarian reserve, and the number of genetically normal embryos available for transfer.
| Patient Age | Success Rate per Cycle | Notes |
|---|---|---|
| Under 30 | 65% – 75% | Highest availability of chromosomally normal embryos |
| 30 – 34 Years | 60% – 70% | Excellent implantation and pregnancy potential |
| 35 – 37 Years | 50% – 65% | PGT results may provide additional information for embryo-selection decisions, depending on the test and clinical circumstances |
| 38 – 40 Years | 40% – 55% | Lower euploid embryo rates may affect outcomes |
| Above 40 Years | 25% – 40% | PGT helps identify the healthiest embryos available |
Embryo Biopsy and Pre-Implantation Genetic Testing (PGT) Cost in Hyderabad
At Fertilica IVF, we believe that patients should have complete clarity regarding treatment costs. The cost of Embryo Biopsy and Pre-Implantation Genetic Testing (PGT) in Hyderabad depends on factors such as the IVF cycle, number of embryos tested, type of genetic analysis required, and laboratory services involved.
Before beginning treatment, our team provides a transparent cost estimate outlining every component of the procedure, ensuring there are no hidden charges.
Factors Affecting Pre-Implantation Genetic Testing (PGT) Cost in Hyderabad?
Several factors can influence the overall cost of PGT treatment, including:
- Fertility consultation and diagnostic evaluation
- IVF or ICSI treatment cycle costs
- Ovarian stimulation medications
- Number of embryos available for biopsy
- Embryo biopsy procedure charges
- Type of PGT performed (PGT-A, PGT-M, or PGT-SR)
- Genetic laboratory testing fees
- Embryo freezing and storage costs
- Frozen embryo transfer (FET) expenses
- Additional genetic counselling sessions
- Advanced reproductive procedures if required
Embryo Biopsy and Pre-Implantation Genetic Testing (PGT) Cost Comparison in India & Worldwide
| Country | Approximate Cost |
|---|---|
| India | ₹2,00,000 – ₹5,00,000 |
| USA | $12,000 – $24,000 |
| UK | £5,200 – £10,400 |
| UAE | AED21,000 – AED42,000 |
| Singapore | SGD9,500 – SGD23,500 |
| City | Approximate Cost |
|---|---|
| Hyderabad | ₹2,00,000 – ₹5,00,000 |
| Bangalore | ₹2,50,000 – ₹5,50,000 |
| Chennai | ₹2,25,000 – ₹5,25,000 |
| Mumbai | ₹3,00,000 – ₹6,50,000 |
| Delhi | ₹2,75,000 – ₹6,00,000 |
Why Consider Fertilica IVF for Embryo Biopsy and PGT in Hyderabad?
Fertilica IVF & Women's Care Center offers fertility consultations and preimplantation genetic testing (PGT) as part of its assisted reproductive services in Hyderabad. Depending on the clinical indication, testing may include PGT-A for chromosome-number abnormalities, PGT-M for specific inherited single-gene conditions, or PGT-SR for certain structural chromosome rearrangements. The treatment process may involve fertility assessment, IVF or ICSI, embryo culture, biopsy, genetic laboratory analysis and counselling about the results. The appropriate testing method depends on the patient's medical history, family history and reproductive goals.
Our fertility team can explain the purpose of testing, the potential benefits and limitations, the expected costs and the available alternatives. Patients can discuss their results with the appropriate fertility and genetics professionals before making decisions about embryo transfer. Fertilica IVF provides fertility consultations at its centres in Banjara Hills and Karmanghat, Hyderabad. The suitability of PGT and the implications of the results should be assessed individually.
Who is Eligible for Embryo Biopsy and Pre-Implantation Genetic Testing (PGT)
Pre-Implantation Genetic Testing (PGT) is recommended for couples and individuals who may have an increased risk of passing genetic conditions to their children or who have experienced repeated fertility treatment challenges. It is commonly advised for women aged 35 years or older, couples with recurrent pregnancy loss, repeated IVF implantation failures, and individuals carrying inherited genetic disorders. PGT is also beneficial for couples with a family history of genetic disease, carriers of single-gene disorders such as thalassemia, patients with chromosomal translocations or other structural chromosomal abnormalities, and couples affected by severe male factor infertility. In addition, individuals pursuing fertility preservation and those wishing to reduce the risk of transmitting inherited genetic conditions to future generations may benefit from this advanced screening. A comprehensive fertility and genetic evaluation is performed before treatment to determine whether PGT is the most appropriate option, helping the fertility team discuss embryo-testing findings, reproductive options and the limitations of screening.
How to Prepare for Embryo Biopsy and Pre-Implantation Genetic Testing (PGT) — Pre-Treatment Checklist
Proper preparation before undergoing Embryo Biopsy and Pre-Implantation Genetic Testing (PGT) helps ensure a smooth treatment experience and supports the best possible outcomes. At Fertilica IVF, our specialists provide comprehensive guidance throughout every stage of the IVF and PGT process.
Medical Preparation
Complete a detailed fertility consultation and reproductive health assessment before starting treatment. This typically includes hormonal blood tests, ultrasound scans, and a review of your medical and fertility history. Your specialist will also evaluate your personal and family genetic history and may recommend genetic carrier screening to identify any inherited conditions that could affect embryo development or future pregnancies.
Treatment Planning
Take time to understand the IVF and PGT treatment timeline, including ovarian stimulation, egg retrieval, embryo development, biopsy procedures, and genetic testing. Discuss the most appropriate type of PGT for your specific circumstances and gain a clear understanding of the potential benefits, expected outcomes, and limitations of genetic testing before proceeding with treatment.
Lifestyle Preparation
Maintain a healthy body weight and follow a balanced diet rich in essential nutrients that support reproductive health. Avoid smoking, alcohol consumption, and recreational substances, as these may negatively impact fertility and embryo quality. Follow all prescribed medications, vitamins, and supplements exactly as instructed by your fertility specialist.
Emotional & Financial Preparation
Attend genetic counselling sessions if recommended to better understand the testing process and possible results. Review treatment costs, laboratory charges, and embryo storage fees so you can plan accordingly. It is also important to prepare emotionally for the testing process and waiting period, and to seek support from your partner, family members, or trusted friends throughout your fertility journey.
Proper preparation, expert laboratory care, and personalized treatment planning canhelp patients understand the procedure, possible results, limitations and follow-up options.
Frequently Asked Questions
Everything you need to know about Embryo-Biopsy And Pre-Implantation Genetic Testing at Fertilica
